产品货号:
Z14964
中文名称:
Cyclin-T1/CCNT1抗体
英文名称:
Anti-Cyclin-T1/CCNT1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Cyclin-T1/CCNT1 Antibody |
指标别名 | CCNT;CCNT1;Cyclin T;cyclin T1;CYCT1;HIVE1 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | CCNT1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Rabbit polyclonal CCNT1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human CCNT1.The immunogen is located within the last 50 amino acids of CCNT1. |
计算分子量 | 81kDa |
成分 | CCNT1 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | CCNT1 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Cyclins function as regulators of CDK kinases and exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event.The cyclin-T1 protein (CCNT1) belongs to the highly conserved cyclin family,whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle.CCNT1 tightly associates with CDK9 kinase,and was found to be a major subunit of the transcription elongation factor p-TEFb.The kinase complex containing CCNT1 and the elongation factor can interact with,and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein,and was shown to be both necessary and sufficient for full activation of viral transcription.CCNT1 and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit. |
Uniprot ID | O60563 |
基因名全称 | Cyclin T1 |
蛋白名全称 | Cyclin T1 |
推荐稀释比 | CCNT1 antibody can be used for detection of CCNT1 by Western blot at 1 ~ 2μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in rat samples and Immunofluorescence in rat samples.All other applications and species not yet tested. |
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